Vincent Racaniello

Quick Facts

Full Name	Vincent Racaniello
Occupation	Author
Date Of Birth	Jan 2, 1953(1953-01-02)
Age	71
Birthplace	Paterson
Country	United States
Birth City	New Jersey
Horoscope	Capricorn

Vincent Racaniello Biography

Vincent Racaniello is one of the most popular and richest Author who was born on January 2, 1953 in Paterson, New Jersey, United States. Vincent R. Racaniello (born January 2, 1953 in Paterson, New Jersey) is a Higgins Professor in the Department of Microbiology and Immunology at Columbia University’s College of Physicians and Surgeons. He is one of the four experts in virology who recently wrote Principles of Virology, a textbook that is used by many teachers of the subject of virology to medical and graduate students.

As a highly respected scientist, Racaniello has received several distinctions, such as Irma T. Hirschl, Searle Scholars, Eli Lilly, Julius Younger and NIH Merit. He is also an Harvey Society Lecturer at Rockefeller University as well as his position as the Hilleman Lecturer for The University of Chicago, and University Lecturer at Columbia University. He will also be the keynote presenter of the American Society for Virology, at its annual meeting in 2018. Racaniello has been as an editor on editorial committees of several scientific journals which include Journal of Virology. Journal of Virology, and is a community editor of the open-access journal PLOS Pathogens. He was also the President of the American Society for Virology and the keynote speaker at their annual meeting in 2017.

Secretion of interferon is one means the body uses to ward off pathogens including viral diseases. However poliovirus is able to replicate when interferon is added to medium used to culture mammalian cells. Racaniello’s laboratory believes that this resistance is dictated by the 2A protein of poliovirus. Racaniello’s laboratory continues to investigate how poliovirus circumvents the immune response of the host enhancing our understanding of its pathogenesis and why it is a disease of the central nervous system.

Humans are the only known natural host for poliovirus. The study of viral disease is therefore only feasible with the generation of a small animal model. Though not susceptible to poliovirus infection, murine cells do allow for efficient replication of poliovirus RNA introduced into the cytoplasm. Taking advantage of this observation, Racaniello’s laboratory constructed the first small animal model of poliomyelitis. Mice producing the human CD155 protein were generated and infected with poliovirus. These mice exhibited all symptoms and pathology of poliomyelitis observed in humans including flaccid paralysis and spinal cord lesions. These mice today are used not only to continue to understand poliovirus pathogenesis but as a means to test the safety of stocks of the polio vaccine.

Although the global elimination of poliovirus started at the time of 1988 poliovirus infecting persists across the globe today the laboratory of Racaniello has started to study the life cycle and pathogenesis of picornaviruses that are similar to poliovirus. These viruses comprise enteroviruses 68 (EV-D68) (EV70) and 68 (EV70) the human rhinovirus as well as coxsackievirus and echovirus 1. Infectious copies of EV70 and a variety of rhinovirus serotypes were developed. The reagents used have been utilized to study how the hosts of viruses is altered, and to determine the cellular proteins required to replicate the virus’s RNA. Racaniello has been studying how these viruses are able to evade the immune system of the host specifically Interferon type I immune response. Infection of the cells of culture by human rhinovirus 1A causes the destruction of the components IPS-1 (MAVS, Cardif). Additionally, a small animal model for virus echovirus 1’s pathogenesis is established.

Vincent Racaniello Net Worth

Vincent Racaniello is one of the richest Author from United States. According to our analysis, Wikipedia, Forbes & Business Insider, Vincent Racaniello 's net worth $5 Million. (Last Update: December 11, 2023)

Racaniello completed his studies at Cornell University in 1974 (BA in biological sciences) and earned his PhD in the lab that was headed by Peter Palese in 1980, researching the genetic reassortment of the influenza virus. As a postdoctoral fellow in the laboratory of David Baltimore located at MIT (1979-1982), Racaniello employed recombinant DNA technology in order to sequence and clone DNA of the tiny animal RNA virus the poliovirus. Utilizing these tools, he created an infectious first clone from an animal RNAvirus. The creation that is infectious has revolutionized the field of virology.

Racaniello started his own research lab in Columbia University in the fall of 1982. The goal of his lab is to investigate the replication and the pathogenesis of small RNA animals viruses Picornaviruses. The life-cycle of a virus starts by entanglement with and entering into the cell’s cytoplasm. His lab discovered CD155 (poliovirus receptor also known as PVR) is a cell-surface protein and a member of the superfamily immunoglobin as being the protein responsible for this process. Knowing how interaction between cells and viruses changes the viral particle and how entry of virus is facilitated through the interaction has allowed us to determine the mechanisms that poliovirus infections are beginning.

Racaniello’s laboratory continues to pursue the fundamental principles of virus biology. Together with a long term collaborator, Racaniello’s lab has determined that neurotropism of enterovirus D68 and Zika virus are not a recently acquired phenotypes. Furthermore, results from their studies examining Zika virus pathogenies revealed a that neocortical development pathologies associated with virus infection may result from architecture defects of the developing brain.

Height, Weight & Body Measurements

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Who is Vincent Racaniello Dating?

According to our records, Vincent Racaniello is possibily single & has not been previously engaged. As of December 1, 2023, Vincent Racaniello’s is not dating anyone.

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Facts & Trivia

Vincent Ranked on the list of most popular Author. Also ranked in the elit list of famous people born in United States. Vincent Racaniello celebrates birthday on January 2 of every year.